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Work Packages

Driving Innovation Across the FH-EARLY Project.

FH-EARLY is structured around 22 Work Packages (WPs), each playing a vital role in achieving the project’s goals. These are grouped into four thematic categories that support three interconnected learning cycles: Data to Knowledge, Knowledge to Performance, and Performance to Data.

Transversal Work Packages (WP1-5 & WP19-22)

Ensuring strong project governance, coordination, and visibility, while embedding ethics and stakeholder engagement throughout:

  • Project management, coordination, and ethics oversight
  • Real-world data infrastructure, variant validation, stakeholder co-creation
  • Communication, dissemination, joint activities, and exploitation
  • Ethics requirements and compliance with EU standards
From Data to Knowledge (WP6–9)

Turning data into insights:

  • Integration of clinical, molecular, and genomic data
  • Understanding of FH-related gene variants and biological mechanisms
  • Development of scoring models and embedding diversity in data interpretation
From Knowledge to Performance (WP10–17)

Driving the development and validation of FH-EARLY’s core solutions:

  • Next-generation chip array
  • Signature biomarker assay
  • AI-powered iPHP platform for risk prediction and co-management
From Performance to Data (Clinical Application) (WP18)

Anchoring the final learning cycle

  • Harnessing of the tools developed through interventional studies focusing on both FH and secondary prevention of cardiovascular disease.
Illustration showing the 22 Work Packages
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The project is funded by the EU
Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or HaDEA. Neither the European Union nor the granting authority can be held responsible for them.
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